Frequently Asked Questions About Methylation Testing

Introduction

Methylation testing is rapidly gaining traction in functional and preventive health circles. But with popularity comes questions—from what it actually measures to how accurate it is and what the testing process looks like.

This FAQ-style article answers the most common queries about methylation testing, including its role in your health journey and what you can expect from an advanced provider like GeneusDNA.

What Is Methylation?

Methylation is a biochemical process that involves transferring a methyl group (CH₃) to molecules like DNA, proteins, and enzymes. It plays a vital role in:

• Gene expression regulation
• Detoxification
• Brain chemistry and mood
• Hormone balance
• Cardiovascular and immune health

What Is Methylation Testing?

Methylation testing assesses how efficiently your body performs methylation-related processes, often by evaluating:

• Genetic markers (e.g., MTHFR, COMT)
• Functional biomarkers (e.g., homocysteine)
• Epigenetic expression (how your genes are currently functioning)

Who Should Consider Methylation Testing?

• Individuals with fatigue, brain fog, or mood disorders
• Those with chronic health issues or unexplained symptoms
• People with a family history of heart disease or autoimmune disorders
• Couples preparing for pregnancy or fertility treatment
• Anyone focused on longevity, detox, or high performance

How Is the Test Performed?

Most methylation tests are done using:

• Saliva swabs or cheek swabs (for genetic variants like MTHFR)
• Blood samples (for homocysteine, folate levels, and epigenetic expression)

GeneusDNA offers a non-invasive, at-home saliva collection kit for your convenience.

Is the Test Accurate?

Yes. Genetic tests for methylation-related genes are highly accurate, especially when using CLIA-certified labs like those partnered with GeneusDNA.

• Gene sequencing for SNPs like MTHFR, COMT, and CBS is >99% accurate.
• Functional markers (e.g., homocysteine) are tested using standardized blood panels.

What Will My Results Include?

With a provider like GeneusDNA, your report will typically cover:

• Methylation gene analysis (e.g., MTHFR, MTR, BHMT, COMT)
• Supplement recommendations based on your genetic variants
• Diet and lifestyle tips to support methylation
• Homocysteine status and B vitamin efficiency
• Personalized methylation protocols

How Long Does It Take to Receive Results?

GeneusDNA results typically take 2 to 4 weeks from the time your sample is received. You’ll be notified when your report is ready via email or app notification.

Is This the Same as a 23andMe or Ancestry Test?

No. While 23andMe focuses primarily on ancestry, GeneusDNA and other methylation-specific tests provide functional health data, personalized protocols, and insights into gene behavior—not just gene presence.

Can I Take Action Based on the Results?

Absolutely. That’s the entire purpose of methylation testing.

• Switch to bioavailable supplements like 5-MTHF and methyl B12
• Adjust your diet to support folate, B vitamins, and detox
• Optimize stress, sleep, and recovery based on your methylation profile

GeneusDNA also provides ongoing support and updates, so your plan evolves as your biology changes.

How Much Does Methylation Testing Cost?

Prices vary depending on the provider and depth of testing. GeneusDNA’s pricing is competitive and includes:

• Full genetic + epigenetic analysis
• Access to 500+ actionable health insights
• Lifetime updates and 1-on-1 doctor consultation

This makes it a cost-effective investment in long-term health and prevention.

Why Choose GeneusDNA?

GeneusDNA specializes in personalized, DNA-driven wellness with:

• Advanced methylation and detox insights
• Customized supplement plans
• Dietary and lifestyle recommendations based on your genes
• A complete digital report accessible anytime

Whether you're biohacking your way to peak performance or resolving long-standing health concerns, GeneusDNA gives you the blueprint to act with precision.

Written by: Dr. Arnond Kitnitchee